William Gahl is the clinical director of the National Human Genome Institute and gave a passionte talk on Rare Diseases at TEDxCMU in April 2011. Powerful imagery and subtle animations caused such a strong reaction in the audience that several audience members contacted the FDA on injustices committed towards patients with rare diseases. The result? The FDA reversed it's old policies and patients who, in the past, could not be treated for their conditions now can.